Wrong dose of Baytril (Please help)

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pinobunny

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My 2.7 kg bunny has snuffles and we took him to the vet.The vet doesn’t know enough with rabbit health and he gave 5 days treatment with 0.18 ml of Baytril (which equals 3.3 mg/kg of enrofloxacin not 10 mg/kg).My bunny improved but not healed completely he still has runny eyes a bit.I now know the safest and most effective treatment plan is 10 mg/kg of enrofloxacin for 14 days.Vet gave low dose medicine and for a short time unfortunately :(. After 5 day treatment,on sixth today, i started enough dose of Baytril which is 0.54 ml.I want to ask can bacterias get resistant from low dose mistaken treatment?I hope it doesn’t effect badly. I up the dose to correct amount now but how many days should i continue?


1 ml of Baytril includes 50 mg of enrofloxacin.He has been taken the medicine with injection form.
 

John Wick

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To clarify, do you mean that you're giving your rabbit injections (i.e. shots) of Baytril? It's not a oral medication? I just flag this because I have never personally heard of baytril being administered via shots, but that doesn't mean it's wrong or anything.

I'm not 100% clear on the timeline/progression here (not necessarily your fault; I get confused once medication concentrations get thrown in), but it sounds like your main concern is whether antibiotic resistance could have been triggered as a result of receiving a relatively low dose over time. Probably yes, but I think the answer is a bit moot at this point since everything has already happened.

Just like with any medical treatment, I would suggest continuing with the Baytril, especially if it seems to be helping, and if it seems like it's no longer working, then discuss trying a different antibiotic. It is not uncommon for people to try different antibiotics to treat an upper respiratory infection because the first or second medication tried wasn't working. Again, it's positive that you saw benefits with Baytril, so I wouldn't stop it if that's the case.
 

pinobunny

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To clarify, do you mean that you're giving your rabbit injections (i.e. shots) of Baytril? It's not a oral medication? I just flag this because I have never personally heard of baytril being administered via shots, but that doesn't mean it's wrong or anything.

I'm not 100% clear on the timeline/progression here (not necessarily your fault; I get confused once medication concentrations get thrown in), but it sounds like your main concern is whether antibiotic resistance could have been triggered as a result of receiving a relatively low dose over time. Probably yes, but I think the answer is a bit moot at this point since everything has already happened.

Just like with any medical treatment, I would suggest continuing with the Baytril, especially if it seems to be helping, and if it seems like it's no longer working, then discuss trying a different antibiotic. It is not uncommon for people to try different antibiotics to treat an upper respiratory infection because the first or second medication tried wasn't working. Again, it's positive that you saw benefits with Baytril, so I wouldn't stop it if that's the case.
Yes we always had injections of baytril and i think injections are better because of the less GI system side effects.I know baytril would work because he improved even on the low dose.But it just concerns me if bacterias get resistent and medicine doesn’t fully clear up the infection because of a mistake :( Do you have any idea what type of antibiotics can i use if now baytril doesn’t clear up the infection because of the resistance?
 

JBun

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Bacteria resistance probably wouldn't have developed in that short of time. So I think now your rabbit is on the proper dose, it should be fine. But you may need to do it much longer than 14 days. Usually for an upper respiratory infection, rabbits should stay on the antibiotic 2 weeks past the last of the symptoms clearing up. So when your rabbit no longer shows symptoms, then give the antibiotics for another 2 weeks minimum. That's what I would do.

If there is no improvement on the first two weeks of antibiotics, or symptoms worsen, then the bacteria may not be sensitive to the baytril any longer. In which case you will need to try a different antibiotic. Maybe something like chloramphenicol or azithromycin. I had good success with azithromycin suspension. My rabbits tolerated it well with no GI problems from it, but some rabbits it can cause GI upset. So just be aware of that risk.

Medirabbit: respiratory issues in rabbits


Injectable baytril can be given by injection, but it just can carry the risk of forming sterile abscesses, especially if not diluted with sterile saline.
 

pinobunny

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Bacteria resistance probably wouldn't have developed in that short of time. So I think now your rabbit is on the proper dose, it should be fine. But you may need to do it much longer than 14 days. Usually for an upper respiratory infection, rabbits should stay on the antibiotic 2 weeks past the last of the symptoms clearing up. So when your rabbit no longer shows symptoms, then give the antibiotics for another 2 weeks minimum. That's what I would do.

If there is no improvement on the first two weeks of antibiotics, or symptoms worsen, then the bacteria may not be sensitive to the baytril any longer. In which case you will need to try a different antibiotic. Maybe something like chloramphenicol or azithromycin. I had good success with azithromycin suspension. My rabbits tolerated it well with no GI problems from it, but some rabbits it can cause GI upset. So just be aware of that risk.

Medirabbit: respiratory issues in rabbits


Injectable baytril can be given by injection, but it just can carry the risk of forming sterile abscesses, especially if not diluted with sterile saline.
Thank you so much!
 
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