This is a few days late, but my current guy is a Hotot x (Mini Lop?) and he is a grump. I have handled him since day one, letting him out of his cage to run around the living room on a regular basis, and having him out on the couch with me either for brushing (for bonding) or just to sit on me and I can pet him. Now he is cage aggressive, if I open his cage to give him food, clean his litterbox, or pet him, he grunts at me and sometimes will lunge at me, scratching and trying to bite (has actually started grunting and lunging at me out of his cage when I'm trying to catch him to put him back in).
My last (and first) rabbit was a Netherland x, and he was sweet. When I would go to pick him up, he would just cower down and lay still, no grunting, or lunging or anything. I could hold him, and pet him, and brush him. When he was out, and I would just say "go back home" and kind of chase him out of where he was, and he would jump back into his cage.
Both males, both neutered, got my 1st one (Thor) at about 5-6 months old, and I have had Louie since he was about 2-3 months old.
Just my 2 cents :happybunny: