You shouldn't really need to change it at this point, the kits will naturally move over a few inches and take the nest with them if it's gets dirty and you can change the bedding around it. If you really feel you have to clean it you can put the kits and nest in a box and scrape out the bedding and any wet hair on the bottom and replace it but save as much of the original nest as possible. Wash your hands first and then give the doe a good rub over, you also might want to take her out while you are moving the nest about but some does don't mind. However, as long as it's not wet and it smells clean you'd be better off waiting a little while longer.