Anyone really familiar with bicillin!?

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Runestonez

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Hey!
I wanted to pick someone's brain regarding bicillin.

We have a 5 year old , 5 pound mini lop with a whomping great dental abscess.
He had his first surgery on it on November 2nd this year.
It involved his jawbone (changes to the cortex of the bone itself)and his two back lower molars on the right side.
The pus was even thicker then regular rabbit abscesses...even the vet was shocked. It was a very aggressive abscess...the vet was surprised Daphne pulled through.
It didn't present as a typical abscess and was invisible on digital x-rays of the jaw.
We did a culture and sensitivity...it came back as Psuedomonas aeruginosa (moderate growth) and e.coli (heavy growth).
The e.coli was no shocker...he had the two rear molars removed through the bottom of his jaw bone leaving an open fissure in his mouth that had to granulate back in.
We were flushing with saline and packing with Baytril soaked gauze...then added oral doses of Chloro Palm to the mix...he seemed to react well to the combo.
However...as the abscess slowly healed (at its worst it could hold nearly 5cc of fluid)...Daphne pulled the gauze out that we were packing it with and it closed up about a week ago.
We had already had quite a bit of the walls slough off...so we continued the Chloro Palm...I checked the sensitivity test and saw that the e.coli was sensitive to Choro and Baytril...but the psuedomonas was resisitant to Chloro and only intermediately affected by Baytril.
So I monitored him for a week and there was no change...in size etc...so we are seeing the vet to have it opened again this week so we can continue treating it...
I am wondering about the bicillin protocol...I think the vet can excise the one lobe of the abscess...but the third lobe looks too close to the musculature of the jaw and will have to be left open for treatment...but I was wondering about using bicillin as a packing agent rather than a SQ injection...

thoughts?

Our appointment is this Tuesday...December 18th!

Thanks
Danielle
 
Hey!
I wanted to pick someone's brain regarding bicillin.

We have a 5 year old , 5 pound mini lop with a whomping great dental abscess.
He had his first surgery on it on November 2nd this year.
It involved his jawbone (changes to the cortex of the bone itself)and his two back lower molars on the right side.
The pus was even thicker then regular rabbit abscesses...even the vet was shocked. It was a very aggressive abscess...the vet was surprised Daphne pulled through.
It didn't present as a typical abscess and was invisible on digital x-rays of the jaw.
We did a culture and sensitivity...it came back as Psuedomonas aeruginosa (moderate growth) and e.coli (heavy growth).
The e.coli was no shocker...he had the two rear molars removed through the bottom of his jaw bone leaving an open fissure in his mouth that had to granulate back in.
We were flushing with saline and packing with Baytril soaked gauze...then added oral doses of Chloro Palm to the mix...he seemed to react well to the combo.
However...as the abscess slowly healed (at its worst it could hold nearly 5cc of fluid)...Daphne pulled the gauze out that we were packing it with and it closed up about a week ago.
We had already had quite a bit of the walls slough off...so we continued the Chloro Palm...I checked the sensitivity test and saw that the e.coli was sensitive to Choro and Baytril...but the psuedomonas was resisitant to Chloro and only intermediately affected by Baytril.
So I monitored him for a week and there was no change...in size etc...so we are seeing the vet to have it opened again this week so we can continue treating it...
I am wondering about the bicillin protocol...I think the vet can excise the one lobe of the abscess...but the third lobe looks too close to the musculature of the jaw and will have to be left open for treatment...but I was wondering about using bicillin as a packing agent rather than a SQ injection...

thoughts?

Our appointment is this Tuesday...December 18th!

Thanks
Danielle
--hi-danielle,,i am not familar with bicillin ( the blood work,cultures dictate most useful antibiotic ),,-i am very pleased the bun came through the anethesia/surgery well--my question is about eating/hays,etc.--or are you still using critical care,???,-abscesses can be hidden or obvious,--arobe or anarobe,,most promenant areas are the face and feet,--watch her poops/ceco,s closely--sincerely james--good job..:highfive:
 
your culture should show whether or not penicillins are the right choice for your bacteria- my guess is not as Pseudomonas is notoriously resistant to all forms of penicillin (Bicillin is just two forms of the same drug (almost the same drug)- a short acting and a longer acting penicillin. Although penicillins are often good empirical antibiotics for many rabbit infections, they rarely do much for Pseudomonas. Were any of the Baytril relatives (e.g. Marbofloxacin) good choices? These can be compounded into a liquid. Amikacin is usually a good drug for Pseudomonas, only it is a bit harsh on the kidneys so you have to make sure your bunny is drinking water really well. Either way, the sensitivities on your culture will help guide you to the best choices. Was a drug like Ceftazedime tested? It sometimes is OK given injectably, but I would only use it if there are no other options.
 
When Sparky went through her dental nightmare 2 years ago, she was treated with a bicillin/zithro combo. I am convinced that this saved her life. I was the one that suggested it to my vet and she readily agreed. My vet is an exotic specialist that has advanced training in dentistry. I know that she would be more than happy to consult with your vet.
 
Hi Danielle - I have a 7 year old English Angora who has had a bad dental abscess along with heavy growth of pseudemonas aeruginosa. I researched here and found great advice from a few years back. It was recommended to me to use a mix of Penicillin and Azithromycin. I had to fight to go this route and now I am finally seeing improvements. My little guy was on Baytril way too long in my opinion. The Pen G injections were given every 2 days for about two weeks and then every 3 days for a few more injections. About 8 days after we stopped, nasal discharge....we now have light growth of pseudemonas aeruginosa (better than heavy), but I think there is still a tooth problem going on, so we are continuing with treatments.....the things I would recommend are to search older posts in this forum and treat aggressively (don't just do Pen injections once a week, not aggressive enough). This is just my experience - hang in there as it is a long process!
 

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