No, there is no reason not to breed her, actually, almost half her litters are because she is very creative getting to the buck and doing the deed in mere seconds without my approval. In commercial meat production a doe is replaced at about 3 years, but max efficiency isn't my concern. Her litters are smaller now, about 6 now, but that's fine with me. She's quite a special rabbit, very headstrong and determined, and best mother I've ever seen - and she's craving for that - isn't that what being a rabbit is all about?You're still breeding her when she is 7 years old??? and she is still producing well. I would have stopped breeding her after she turned 3. I'm surprised she wouldn't be tired of breeding by now.