If you don't keep your bun's nails trimmed, it could lead to sore hocks. This is VERY painful for your bunny.
You should get your bunny use to being held at least once a week for minor check ups from you!!!
Weekly brushing, teeth check, ear check, fur check, butt check, AND nail check!!! If you do this on a weekly basis, you won't need to pay for expensive medical bills in the future.
Oh yeah, after I finish doing my weekly checks with my bun buns, I immediately give them ONE PLAIN Cheerio. This keeps them happy and let's them know that EVERYTHING is OK "o)